A 50-year-old man is admitted into the gastroenterology ward, following severe right upper quadrant pain, jaundice, nausea and vomiting. A set of values are recorded: Core Body Temperature: 38.7 °C Blood Pressure: 117/83 mmHg Heart Rate: 78 bpm A diagnosis of Ascending Cholangitis is made. This condition is characterised by the presence of gallstones impacted within the common bile duct of the biliary tree.